Morphogenesis

Active perception during angiogenesis: filopodia speed up Notch selection of tip cells in silico and in vivo

This study demonstrates that filopodia speed up collective endothelial decisions during angiogenesis by conferring a bistable switch-like property to Notch lateral inhibition, ensuring rapid and robust tip cell selection.

Feb 2, 2021

A circuit basis for morphogenesis

This paper explores the consequences of a circuit basis for reaction–diffusion systems on morphogenesis, including the reachability of patterns and the logical basis of pattern stability.

May 23, 2016

Can active perception generate bistability? Heterogeneous collective dynamics and vascular patterning

This study explores the role of active perception in generating bistability during angiogenesis. By examining endothelial cells (ECs) in a simulated environment, the study demonstrates that sensorimotor feedback can lead to bistability and influence collective decision timing.

Jul 30, 2014