This study identifies temporal regulation of the VEGF/Notch feedback loop as a key mechanism in determining vascular network density, using computational modeling and in vivo live imaging to show how the rate of tip-cell selection influences network topology.
Feb 24, 2016
This paper presents a new algorithm for the evolution of artificial gene regulatory networks (GRNs), using a network distance metric for speciation and genetic similarity. The algorithm is inspired by the neuroevolution of augmenting topologies (NEAT) algorithm and demonstrates superior performance compared to standard GA and evolutionary programming across various experiments.
Jan 23, 2015
This mini-review discusses the eco-evolutionary dynamics of complex social strategies in microbial communities, focusing on cooperation, competition, and cheating behaviors.
Feb 25, 2014
This mini-review discusses the eco-evolutionary dynamics of complex social strategies in microbial communities, focusing on cooperation, competition, and cheating behaviors.
Feb 25, 2014
Environmental light suppresses the wake-promoting effects of dopamine in fly brains. A subset of clock neurons, the 10 large lateral-ventral neurons (l-LNvs), are wake-promoting and respond to dopamine, octopamine as well as light. Behavioral and imaging analyses suggested that dopamine is a stronger arousal signal than octopamine. Light exposure not only suppressed the l-LNv responses but also synchronized responses of neighboring l-LNvs. The regulatory mechanisms described here may contribute to the control of sleep stability while still allowing behavioral flexibility.
Aug 22, 2011
This article introduces evolutionary computation in the arts, focusing on the evolution of music-making systems using genetic programming. It discusses challenges in fitness assessment and experiments with evolving music-producing virtual organisms.
May 1, 2005