Complex population dynamics in a spatial microbial ecosystem with Physarum polycephalum
This study explores the interactions between Physarum polycephalum and a red yeast in a spatial ecosystem, revealing an inverse growth relationship and successional dynamics, using advanced image analysis for semantic segmentation.
Jul 18, 2021
SNT: a unifying toolbox for quantification of neuronal anatomy
SNT is a comprehensive framework for neuronal morphometry and connectomics, providing tools for tracing, proof-editing, visualization, quantification, and modeling of neuroanatomy, available via Fiji's ImageJ distribution.
Apr 1, 2021
Active perception during angiogenesis: filopodia speed up Notch selection of tip cells in silico and in vivo
This study demonstrates that filopodia speed up collective endothelial decisions during angiogenesis by conferring a bistable switch-like property to Notch lateral inhibition, ensuring rapid and robust tip cell selection.
Feb 2, 2021
Tales from the Trenches: Developing sciview, a new 3D viewer for the ImageJ community
This paper describes the development of sciview, a modern 3D viewer for the ImageJ community, highlighting sustainable development, community building, and software engineering best practices.
Apr 28, 2020
Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy
This study uses light-sheet fluorescence microscopy (LSFM) to demonstrate improved imaging techniques for mouse models of eye diseases, revealing new pathological features and offering advancements in understanding neurovascular and degenerative processes.
Feb 19, 2020
A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage
Actively cycling epithelial progenitors in the mouse incisor generate enamel-producing ameloblasts and non-ameloblast cells, coordinating tissue renewal and repair through progenitor-cell proliferation and Notch1-mediated cell conversion.
Sep 1, 2019
Multi-sample SPIM image acquisition, processing and analysis of vascular growth in zebrafish
We present a workflow for multi-sample SPIM imaging, processing, and analysis to study vascular growth in zebrafish, allowing simultaneous imaging and automated data processing, yielding precise quantification of vascular development.
Mar 20, 2019
Artificial Gene Regulatory Networks—A Review
A review of computational models of gene regulatory networks, covering modelling techniques and their application to control dynamics, evolutionary algorithms, morphogenesis, and neuromodulation.
Nov 1, 2018
FunImageJ: a Lisp framework for scientific image processing
FunImageJ is a Lisp framework for scientific image processing built upon the ImageJ software ecosystem, offering a functional programming style and performance suitable for big data biological image analysis.
Feb 26, 2018
Asymmetric division coordinates collective cell migration in angiogenesis
Asymmetric division in endothelial tip cells generates daughters of distinct sizes and Vegfr signalling levels, driving coordinated collective cell migration in angiogenesis. This Dll4/Notch-independent mechanism integrates cell proliferation with migration, potentially aiding tissue growth during development, regeneration, and cancer invasion.
Dec 1, 2016